Section Gene Symbol Age Orientation Objective Veracity Veracity Support 11 glutamate receptor, ionotropic, AMPA2 (alpha 2) Gria2 P7 Sagittal 10X Confirmed Multiple Lines Match Matches In Situ Data Supported by Literature

BX BAC Address marker BX726 RP23-437P19 EGFP

Other cross-sections of this brain: 01 02 03 04 05 06 07 08 09 10 11 (thumbnails not to scale)

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Add this image to your album Download this image at the scale shown below. Founder Line: DP5 See all MMRRC strains for : Gria2 Get this mouse from MMRRC: STOCK Tg(Gria2-EGFP)DP5Gsat/Mmucd: Details, Order Get this BAC Clone from CHORI: BX726 UCSC Genome Browser for this BAC Address: RP23-437P19

Read gene expression annotations for this image View other image sets for Gria2

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Comment on this Gene: According to the literature, Gria2 is the most widely expressed subunit among the four subunits. Its expression reaches highest level in the first postnatal week and then reduces to lower level in adult. The BAC data is incomplete. The confirmed expression sites are cerebellum (Purkinje cells), hippocampus, MOB and cortex. But compared with BGEM in situ data, weak or little expression is seen in striatum, thalamus and dorsal spinal cord at P7, weak expression in hypothalamus, cortex and striatum at adult.

Gene Expression Annotations for this image

structure	Expression Level	Expression Pattern	Cell types	Subtypes
Olfactory Bulb	moderate to strong signal	region-specific	neuron	granule cell of MOB periglomerular cell of MOB other
Cerebral cortex	moderate to strong signal	region-specific and scattered	neuron
Septum	moderate to strong signal	scattered	neuron	fibers
Ventral striatum	moderate to strong signal	region-specific and scattered	neuron	fibers
Basal Forebrain	moderate to strong signal	scattered	neuron	fibers
Thalamus	weak signal	region-specific and scattered	neuron	fibers
Hypothalamus	moderate to strong signal	region-specific and scattered	neuron
Midbrain	moderate to strong signal	region-specific and scattered	neuron
Pons	moderate to strong signal	region-specific and scattered	neuron	fibers
Medulla	moderate to strong signal	region-specific and scattered	neuron	motor neuron fibers other
Cerebellum	moderate to strong signal	region-specific	neuron	Purkinje cell

Other image sets for Gria2

age	orientation	Acquisition technique	Founder Line	Batch
adult	Horizontal	brightfield	DP5	3 images
adult	Sagittal	brightfield	DP5	10 images
adult	Sagittal	confocal	DP5	1 images
P7	Horizontal	brightfield	DP5	3 images
P7	Sagittal	brightfield	DP5	11 images
P7	Sagittal	confocal	DP5	1 images
P7	Sagittal	confocal	DP5	1 images
P7	Sagittal	confocal	DP5	1 images
E15.5	Horizontal	brightfield	DP5	3 images
E15.5	Sagittal	brightfield	DP5	10 images

BGEM Probe	Related ISH images
Gria2	223

Supporting literature:

PubMed ID
7884041
9600387
8450957
7476026

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Veracity	definition
Confirmed	Confirmed refers to genes in which multiple lines yield matching datasets that agree with the available literature, or in which a single line has been produced that matches the available literature. In those cases where there a discrepancy between the literature and the reporter gene data (missing or additional sites of expression), this is noted in the database.
To Be Confirmed	To be confirmed refers to genes in which multiple lines produce matching datasets, but for which no independent expression data is available.
Anomalous	Anomalous refers to data collected from BAC reporter constructs producing different expression patterns in different lines (i.e. position effects).

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